MEPS

MEPS (patent pending) performs the same function as SPE, namely the purification or speciation of samples, but with some significant differences:

  • MEPS works with much smaller samples (as small as 10µL) than full scale SPE
  • MEPS can be fully automated – the sample processing, extraction and injection steps are performed on-line using the same syringe
  • MEPS is applicable to GC and LC
  • Significantly reduces the volume of solvents and sample needed

Peter Dawes, chairman of SGE Analytical Science, speaks to "The Column" about the benefits & applications of this novel approach.  Read more...

To view an animated presentation on MEPS click here.

Sample Size and Sensitivity:

Sample volumes as small as 10µL can be used or larger samples, 1mL or more, may be concentrated by taking multiple aliquots of 100µL or 250µL.

Re-useable

Typical BIN life is conservatively about 40-100 samples but actual life is dependant on the sample matrix. The small quantity of phase in the MEPS BIN can be easily and effectively washed between samples which removes the possibility of carry-over. This process simply is not practical on conventional SPE devices.

Flexible and easy to use:

MEPS BINs are available in a variety of common SPE phases. The dimensions of the sorbent bed ensure that the sorbent performance remains identical to conventional SPE devices used for extraction of similar samples

Sample preparation for complex biological samples is readily adapted to MEPS and reduces the volume of sample and reagents required for extraction when compared with conventional SPE and other "micro extraction procedures".

The MEPS approach to sample preparation is suitable for reversed phases, normal phases, mixed mode and ion exchange chemistries. Because MEPS BINs can be used for sample volumes as small as 10µL it makes them particularly well suited to on-line use with LC-MS analysis of volume limited samples.

How to choose your product:

Choose your MEPS syringe

The current range of syringes may be used manually or in CTC Analytics, HTA 300APlus and Varian 8400 auto-injectors.

Choose your SPE BIN's

BINs are available in needle styles to suit LC and GC applications. Needles are packed in a sealed blister pack of 5 needles to ensure their integrity.

 

 MEPS Syringes
 
Part no. Description Scale
(mm)
Barrel
OD (mm)
Volume
(µL)
005291100µL Removable needle MEPS syringe for CTC Analytics, HTA 300APlus, Thermo Scientific & Varian 8400 systems60 6.7 100
006291250µL Removable needle MEPS syringe for HTA 300APlus, Thermo Scientific & Varian 8400 systems60 6.7 250
006292250µL Removable needle MEPS syringe for CTC Analytics systems60 7.8 250

MEPS BINs   

For GC applications: needle is 23 gauge, 0.63mm OD, cone point style

Part no. Description Phase For use with MEPS
Syringe Part No.
Pack
Size
2900101MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsC18 005291 and 006291 5
2900102MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsSilica 005291 and 006291 5
2900103MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsC8+SCX 005291 and 006291 5
2900104MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsC2 005291 and 006291 5
2900106MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsC8 005291 and 006291 5
2900105MEPS Development kit for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systems
(contains 1 each of C18, C8, C2, SILICA and C8+SCX)
005291 and 006291 5
2900301MEPS BIN for CTC Analytics systems using 250µL syringesC18 006292 5
2900302MEPS BIN for CTC Analytics systems using 250µL syringesSilica 006292 5
2900303MEPS BIN for CTC Analytics systems using 250µL syringesC8+SCX 006292 5
2900304MEPS BIN for CTC Analytics systems using 250µL syringesC2 006292 5
2900306MEPS BIN for CTC Analytics systems using 250µL syringesC8 006292 5
2900305MEPS Development kit for CTC Analytics systems using 250µL syringes
(contains 1 each of C18, C8, C2, SILICA and C8+SCX)
006292 5

For LC applications: needle is 22gauge, 0.72mm OD, LC point style

Part no. Description Phase For use with MEPS
Syringe Part No.
Pack
Size
2900401MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsC18 005291 and 006291 5
2900402MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsSilica 005291 and 006291 5
2900403MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsC8+SCX 005291 and 006291 5
2900404MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsC2 005291 and 006291 5
2900406MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsC8 005291 and 006291 5
2900405MEPS Development kit for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systems
(contains 1 each of C18, C8, C2, SILICA and C8+SCX)
005291 and 006291 5
2900408MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsSCX 005291 and 006291 5
2900409MEPS BIN for HTA 300APlus, Thermo Scientific, Varian 8400 and 100µL CTC Analytics systemsSAX 005291 and 006291 5
2900501MEPS BIN for CTC Analytics systems using 250µL syringesC18 006292 5
2900502MEPS BIN for CTC Analytics systems using 250µL syringesSilica 006292 5
2900503MEPS BIN for CTC Analytics systems using 250µL syringesC8+SCX 006292 5
2900504MEPS BIN for CTC Analytics systems using 250µL syringesC2 006292 5
2900506MEPS BIN for CTC Analytics systems using 250µL syringesC8 006292 5
2900505MEPS Development kit for CTC Analytics systems using 250µL syringes
(contains 1 each of C18, C8, C2, SILICA and C8+SCX)
006292 5
2900508MEPS BIN for CTC Analytics systems using 250µL syringesSCX 006292 5
2900509MEPS BIN for CTC Analytics systems using 250µL syringesSAX 006292 5

Base material is silica with mean particle size of 45µm and pore size of 60Å.