Problem Area 1 - The Injector

 

Problem Area 1 - The Injector

  • Do not heat until purged with oxygen- free gas (10 volumes)
  • Always note injector and detector ends
  • Always cut end of column after passing through ferrule
  • Consider column dimensions and phase
  • Consider the use of pre- column
  • Set correct flow rate using linear carrier gas velocity
  • Do not overheat column unnecessarily
  • Use good quality ferrules and change as needed
  • Support the column cage in the oven
 


 

Carrier Gas

  • always use high quality gases
  • use and regularly change gas filters
  • use good quality cleaned tubing

Septa

  • choose high quality low bleed septa
  • change septa regularly
  • consider tip style of syringe needle



Other items to consider

  • column connection
  • injection technique
  • injection temperature
  • solvent used
  • split flow
  • splitless time
 
 

Syringe

  • use the correct one for the injector
  • clean the syringe regularly
  • never inject less than 20% full scale
 

Injection liner

  • consider liner design
  • change liner regularly